Dr Odetola Amoo Amos   (Published 2019)

Dr Amoo Amos
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        Anatomy Department    

                      ANA 201 General Embryolgy



Instructor: Dr. Odetola Amos A.,

Lectures: Friday, 10 am- 12pm, LT1, phone: (+234) 8032072958

Office hours: Thursday, 1.30 to 2.30 PM, Office:



General overview of lecture: The course introduces some fundamental concepts in developmental anatomy including molecular regulation and signaling, gametogenesis, pre-fertilization, fertilization, cleavage, implantation, bilaminar germ disc and gastrulation (Trilaminar germ layer stage).


Prerequisite: The students are expected to have a strong background in the basic biology, particularly about the reproductive system.. Some knowledge of genetics will be of great importance in understanding some concepts of teratology.


Learning outcomes: At the completion of this lecture, students should be able to:

  • Enumerate various regulatory molecules that are involved in organogenesis
  • describe the cell division
  • mention the source of the primordial germ cells
  • state the incident or occurrences during the 2nd week of development
  • explain ovarian cycle, fertilization, cleavage and implantation in details
  • understand the principles of teratology


Assignments: students are going to have three (2) individual and one (1) group assignments throughout the course in addition to a Mid-Term Test and a Final Exam. Assignments are organized and structured as preparation for the midterm and final exam, and are meant to be a studying material for both exams.

Grading: We will assign 10% of this class grade to homeworks, 10% for the programming projects, 10% for the mid-term test and 70% for the final exam. The Final exam is comprehensive.





Textbook: The recommended textbook for this class are as stated:

Title: Langman’s Medical Embryology

Author: T.W. Sadler

Publisher: Wolters Kluwer Health

ISBN: 978-1-4511-9164-6


Title: Larsen’s Human Embryology

Authors: Gary C.S., Steven B.B., Philip R.B., and Philippa H.F.

Publisher: Churchill Livingstone

ISBN: 978-1-4557-0684-6


Title: The Developing Human, Clinically Oriented Embryology 8th Ed.

Author: K.L. Moore and T.V.N.Persaud

Publisher: Saunders


Courseware: ANA 201 General Embryology

The following documents outline the courseware for the course ANA 213 General Embryology. Much of this material is taken from recommended text books.

1:Introduction to Molecular Regulation and Signaling

  • Gene Transcription
  • Other regulation of gene expression
  • Induction and Organ formation
  • Cell signaling
  • Key Signaling Pathways for Development


  • What is Gametogenesis?
  • What is gamete and why the study of gamete?
  • Primordial Germ Cells
  • Chromosomal theory of inheritance
  • Morrphological changes during maturation of the gametes:Spermatogenesis& Oogenesis

3: First week of Development.

  • Ovarian cycle
  • Fertilization
  • Cleavage
  • Blastocyst formation


4: Second Week of Development: Bilaminar Germ Disc

  • Differentiation of trophoblast into cytotrophoblast and syncytiotrophoblast
  • Development of foetal membranes
  • Formation of two cavities: Amniotic and Chorionic cavities
  • Formation of somatic and splanchnic mesoderm

5: Third Week of Development

  • Gastrulation: formation of embryonic mesoderm and endoderm
  • Formation of the Notochord
  • Establishment of the body axes
  • Growth of the embryonic disc

6: 3rd to 8th Week of Development

  • Derivatives of Ectodermal Germ Layer
  • Derivatives of Mesodermal Germ Layer
  • Derivatives of Endodermal Germ Layer
  • Patterning of the Anteroposterior Axis


Item Type: Courseware(non-copyrighted, full text)
Format: PDF document,   151.97 KB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: anatomy
Department: Medicine and Surgery
Field of Study: Human Anatomy
Uploaded By: Uwaifo Ferdinand
Date Added: 31 Jan 2019 2:34pm
Last Modified: 31 Jan 2019
courseware URL:

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