ABSTRACT
Background: The influences of tribes on coagulation profile have not been sufficiently investigated. However, Genetic factors contribute to the inter individual variation of blood coagulation protein levels (de Lange et al., 2001). This study was aimed to assess some coagulation profile on 420 subjects, age range 18-84years old, consisting of 60 subjects each from the different tribes (Igbo, Yoruba, Hausa, Ibibio, Ijaw, Urhobo and Efik) males and females all residing in Nnewi town, Anambra state Nigeria. Prothrombin Time (PT), Activated Partial Thrombin Time (APTT), Whole blood Clothing Time (CT) and Bleeding Time (BT) were measured among 7 different tribes (Igbo, Yoruba, Hausa, Ibibio, Ijaw, Urhobo and Efik) residing in Nnewi, Anambra state Nigeria. Prothrombin Time (PT) and Activated Partial Thrombin Time (APTT) values showed significant different (p<0.05) among the tribes, while Whole blood Clothing Time (CT) and Bleeding Time (BT) showed no significant different (p>0.05) among the different tribes. We conclude that tribe (ethnicity) had effect on Prothrombin Time (PT) and Activated Partial Thrombin Time (APTT) values.