Abstract:
Background: Carbapenems are a class of ? lactam antibiotics with broad antibacterial activity. However, the increasing use of the drug class has resulted in varied susceptibility pattern of Pseudomonas aeruginosa thus limiting treatment options. Aims: The study was done to determine the carbapenem susceptibility pattern and to detect novel class 1 integron of the metallo-beta-lactamase genes among Pseudomonas aeruginosa isolates from clinical specimens in South Eastern Nigeria. Settings and Duration of Study: The study was carried out in South Eastern Nigeria with all experimental works done in Nnamdi Azikiwe University Teaching Hospital, Nigeria from June 2012 – January 2013