COMPARATIVE STUDIES ON THE EFFECT OF EXTRACTS OF CYMBOPOGON CITRATUS (LEMON GRASS) ON THE LIPID PROFILES OF WISTAR ALBINO RATS

Prof Usunobun Usunomena and Adegbegi J. Ademuyiwa , Anyanwu, G. Olubunmi, Onoagbe O. Iyere   (Published 2016)

Prof Usunomena
See Profile Page

Abstract

ABSTRACT
Plants  of  medicinal  properties  have  been  recognized  to  have
therapeutic  effects  as  well  as  toxic  side  effects.  The  present  study
aimed  to  investigate  the  effect  of  aqueous  and  ethanolic  extracts  of
Cymbopogon  citratus  on the  lipid  profiles  of  normal  rats. The  lipid
profiles  of  rats  treated  with  both  ethanolic  and  aqueous  extracts  of
lemon  grass  as  observed  in  table  3.  The  Total  cholesterol,
Triglycerides,  High  density  lipoprotein  (HDL)  and  low  density
lipoprotein  (LDL)  levels  of  the  ethanolic  extracts  were  observed  to  be
significantly  lowered  when  compared  with  the  aqueous  extract  and  the
control  normal  rats. The  results  of  the study  also  showed  that  the level
of  the  LDL-Cholesterols  in  both  ethanolic  and  aqueous  extracts  were  decreased  but  not
significantly  (p<0.05)  different  when  compared  with  the  control  group  and  the  level  of  the
HDL-Cholesterol  in  the  treated  groups.  Thus,  blood  serum  cholesterol  level  was  found  to  be
down  regulated  in  this  study. Findings  in  this  study  showed  that  this  plant  did  not  exert
oxidative  damage;  in  some  instances,  particularly  in  the  liver,  kidney  and  pancreas as  well  as
its  relative  safety  and possible  use for  weight  gain.


Item Type: Journal article(non-copyrighted)
Format: PDF document,   374.05 KB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: medicinal plants; lipid profiles; Cymbopogon citratus; rats; oxidative status.
Department: Natural Science
Field of Study: Biochemistry
Uploaded By: Imarhiagbe Odoligie
Date Added: 22 Nov 2017 11:08am
Last Modified: 22 Nov 2017
Journal URL: https://www.edouniversity.edu.ng/oer/journal/comparative_studies_on_the_effect_of_extracts_of_cymbopogon_citratus_lemon_grass_on_the_lipid_profiles_of_wistar_albino_rats


Google Docs     Print     Download