ESSENTIAL TRACE METALS AND TOTAL ANTIOXIDANT POTENTIAL IN THE BREAST MILK AND PLASMA OF NIGERIAN HIV-INFECTED LACTATING MOTHERS
Dr Rahamon Sheu Kadiri and Akiibinu MO, Arinola OG (Published 2013)
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Rahamon SK, Akiibinu MO, Arinola OG. Essential Trace metals and Total Antioxidant Potential in the breast milk and plasma of Nigerian HIV-infected lactating mothers. Journal of Research in Medical Sciences 2013; 18 (1): 27-30.
Background: The effect of Human Immunodeficiency Virus (HIV) on the immune system is well documented however; its impact on the nutritional and immunological qualities of the breast milk is scarce.
Aim: Levels of some essential trace metals, albumin and antioxidant status in the plasma and breast milk of Nigerian HIV-infected lactating mothers were determined.
Materials and Methods: Essential trace metals and total antioxidant potential were measured using spectrophotometric method while albumin was measured using single radial immunodiffusion technique.
Results: Only the mean plasma level of albumin in HIV infected lactating mothers (HIM) was significantly reduced when compared with HIV free lactating mothers (HFM) [9.39 (4.46) g/L vs 26.18 (18.43) g/L, P=0.000], others had no significant difference. The mean breast milk levels of total antioxidant potential (1776.82(564.26) µmolTE/L vs. 2384.67 (679.00) µmolTE/L, P = 0.0000), Cu [67.68 (5.04) µg/dL vs. 71.10 (5.45) µg/dL, P = 0.033] and Fe [66.21 (6.31) µg/dL vs. 71.20 (6.48) µg/dL, P = 0.011] were significantly reduced in HIM compared with HFM. No significant differences were observed in other parameters.
Conclusion: It could be concluded from this study that hypoalbuminemia is a feature of HIV-infected lactating mothers and that breast milk of HIM has low antioxidant capacity.
|Item Type:||Journal article(non-copyrighted)|
|Format:||PDF document, 826.95 KB|
|Keywords:||Breast milk, essential trace metals, human immunodeficiency virus, lactating mothers, total antioxidant potential|
|Field of Study:||Biochemistry|
|Uploaded By:||Uddin Osemengbe Oyaimare|
|Date Added:||02 Nov 2017 11:33am|
|Last Modified:||22 Nov 2017|
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