ESSENTIAL TRACE METALS AND TOTAL ANTIOXIDANT POTENTIAL IN THE BREAST MILK AND PLASMA OF NIGERIAN HIV-INFECTED LACTATING MOTHERS

Dr Rahamon Sheu Kadiri and Akiibinu MO, Arinola OG   (Published 2013)

Dr Sheu Kadiri
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Abstract

Rahamon SK, Akiibinu MO, Arinola OG. Essential Trace metals and Total Antioxidant Potential in the breast milk and plasma of Nigerian HIV-infected lactating mothers. Journal of Research in Medical Sciences 2013; 18 (1): 27-30.

 

 

ABSTRACT

Background: The effect of Human Immunodeficiency Virus (HIV) on the immune system is well documented however; its impact on the nutritional and immunological qualities of the breast milk is scarce.

Aim: Levels of some essential trace metals, albumin and antioxidant status in the plasma and breast milk of Nigerian HIV-infected lactating mothers were determined.

Materials and Methods: Essential trace metals and total antioxidant potential were measured using spectrophotometric method while albumin was measured using single radial immunodiffusion technique.

Results: Only the mean plasma level of albumin in HIV infected lactating mothers (HIM) was significantly reduced when compared with HIV free lactating mothers (HFM) [9.39 (4.46) g/L vs 26.18 (18.43) g/L, P=0.000], others had no significant difference. The mean breast milk levels of total antioxidant potential (1776.82(564.26) µmolTE/L vs. 2384.67 (679.00) µmolTE/L, P = 0.0000), Cu [67.68 (5.04) µg/dL vs. 71.10 (5.45) µg/dL, P = 0.033] and Fe [66.21 (6.31) µg/dL vs. 71.20 (6.48) µg/dL, P = 0.011] were significantly reduced in HIM compared with HFM. No significant differences were observed in other parameters.

Conclusion: It could be concluded from this study that hypoalbuminemia is a feature of HIV-infected lactating mothers and that breast milk of HIM has low antioxidant capacity.


Item Type: Journal article(non-copyrighted)
Format: PDF document,   826.95 KB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: Breast milk, essential trace metals, human immunodeficiency virus, lactating mothers, total antioxidant potential
Department: Natural Science
Field of Study: Biochemistry
Uploaded By: Uddin Osemengbe Oyaimare
Date Added: 02 Nov 2017 11:33am
Last Modified: 22 Nov 2017
Journal URL: https://www.edouniversity.edu.ng/oer/journal/essential_trace_metals_and_total_antioxidant_potential_in_the_breast_milk_and_plasma_of_nigerian_hiv-infected_lactating_mothers


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