EVALUATION OF TOTAL BILE ACID AND AMINOTRANSFERASES IN HIV/AIDS PATIENTS WITH COINFECTION OF HEPATITIS B ANDC VIRUSES

Prof Olaniyan Mathew Folaranmi   (Published 2019)

Prof Mathew  Folaranmi
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Abstract

Abstract Patients confirmed to be seropositive for human immunodeficiency Virus (HIV) infection by Western blot technique attending Baptist Medical Centre, Saki, Oyo state-Nigeria were studied; including 30 males; 30 females; 20HIV mono-infected, 20HIV-HBV co-infected, 20HIV-HCV co-infected subjects aged 16 to 65 years. Age and sex matched apparently healthy HIV, HCV and HBV seronegative, subjects (N=50) consisting of 25 (50%) males and 25 (50%) females were recruited as controls. Plasma ALT, AST and Total Bile Acids were determined in the subjects biochemically by spectrophotometry. Antibody to hepatitis C virus and surface antigen to hepatitis B virus was determined in the subjects immunochemically by ELISA. The result obtained showed a significantly higher mean value of plasma ALT,AST and Total Bile Acids in HIV patients co-infected with hepatitis B or C virus than the values obtained in the control subjects(p<0.01). There was a significantly higher mean value of AST in the HIV mono-infected than the result obtained from the control subjects with p


Item Type: Journal article(non-copyrighted)
Format: PDF document,   218.06 KB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: MEDICAL LABORATORY SCIENCE
Department: Medical Laboratory Science
Field of Study: Medical Laboratory Science
Uploaded By: Uwaifo Ferdinand
Date Added: 25 Feb 2019 3:31pm
Last Modified: 25 Feb 2019
Journal URL: https://www.edouniversity.edu.ng/oer/journal/evaluation_of_total_bile_acid_and_aminotransferases_in_hivaids_patients_with_coinfection_of_hepatitis_b_andc_viruses


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