METABOLIC ALTERATIONS IN DIFFERENT STAGES OF HYPERTENSION IN AN APPARENTLY HEALTHY NIGERIAN POPULATION 2018/2019

Dr Rahamon Sheu Kadiri and M. A. Charles-Davies,1 A. A. Fasanmade,2 J. A. Olaniyi,3 O. E. Oyewole,4 M. O. Owolabi,2 J. R. Adebusuyi,5 O. Hassan,5 M. T. Ajobo,6 M. O. Ebesunun,7 K. Adigun,8 K. S. Akinlade,1 U. A. Fabian,1 O. O. Popoola,1 S. K. Rahamon,1 W. Okunbolade,1 M. A. Ogunlak   (Published 2018)

Dr Sheu Kadiri
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Abstract

Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS
components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian
traders aged 18–105 years were participants of a cohort study.The International Diabetes Federation (2005) and the National High
Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively.
Anthropometric indices were obtained by standard methods. Levels of fasting plasma glucose (FPG), total cholesterol (TC),
triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low-density
lipoprotein cholesterol (LDLC) was calculated. Data analysed statistically were significant at ???? < 0.05. 143 (26.8%), 197 (36.9%),
and 194 (36.3%) of the traders had normotension, pre-HTN and HTN (stages 1 and 2), respectively. All indices tested except HDLC
were significantly different among BP groups (???? < 0.05).Waist to hip (WHR) and waist to height (WHT) ratios were significantly
different between HTN groups (???? < 0.05). HTN was associated with MS and female gender (???? < 0.05). Metabolic alterations
and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable
metabolic factors may be necessary to reduce MS and high BP.


Item Type: Journal article(non-copyrighted)
Format: PDF document,   1.27 MB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: BIOCHEMISTRY
Department: Natural Science
Field of Study: Biochemistry
Uploaded By: Uwaifo Ferdinand
Date Added: 10 Mar 2019 12:22am
Last Modified: 09 Mar 2019
Journal URL: https://www.edouniversity.edu.ng/oer/journal/metabolic_alterations_in_different_stages_of_hypertension_in_an_apparently_healthy_nigerian_population_20182019


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