The aim of this study is to review a procarcinogen, the N-Nitrosodimethylamine (NDMA), liver and
kidney functional enzymes (in assessing action of toxicant s such as NDMA) as well as oxidative stress parameters
(in assessing the extent of free radical damage and scavenging). Catalase and hydro peroxidase enzymes convert
hydrogen peroxide and hydro peroxides to non-radical forms and functions as natural antioxidant in human body.
Enzymes like Superoxide Dismutase (SOD) and Catalase (CAT) and compounds such as tocopherol and ascorbic
acid can protect organisms against free radical damage. Lipid peroxidation is a mechanism generally recognized as
being the most important in the pathogenesis of liver injury by a number of toxic compounds including NDMA.