PHYTOCHEMICAL SCREENING, MINERAL COMPOSITION AND IN VITRO ANTIOXIDANT ACTIVITIES OF PTEROCARPUS MILDBRAEDII LEAVES
Prof Usunobun Usunomena and Igwe V. Chinwe (Published 2016)
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Background: Pterocarpus mildbraedii is used in some Nigerian tribes in the treatment of headaches, pains, fever, convulsions, and res-piratory disorders. This study was carried out to ascertain the phytochemicals, minerals and in vitro antioxidant activities of Pterocarpus
Methods: Qualitative phytochemical screening was carried out using standard procedures while Mineral analysis was carried out using
Atomic Absorption Spectrophotometer (AAS). Also, antioxidant activities of Pterocarpus mildbraedii leaves were evaluated using re-ducing power ability and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays.
Results: Result on phytochemicals reveals the presence of flavonoids, saponins, alkaloids, tannins. Mineral analysis showed calcium
(1283mg/kg) to be higher in concentration and manganese (4mg/kg) least in concentration (4mg/kg). Other analysed minerals include
sodium (603mg/kg), potassium (1048mg/kg), magnesium (778mg/kg), zinc (25mg/kg), iron (146mg/kg), phosphates (1002mg/kg), etc.
In vitro antioxidant activity results show that Pterocarpus mildbraedii possess potent but dose-dependent reducing power ability and free
radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals.
Conclusion: The presence of phytochemicals such as flavonoids, saponins, alkaloids and tannins in Pterocarpus mildbraedii provides
some biochemical basis for the ethno pharmacological uses of the plant. Also the information provided in this research study may help to
spread the ethno botanical uses of Pterocarpus mildbraedii leaves to other parts of the World. The findings clearly demonstrate that
Pterocarpus mildbraedii leaves have promising antioxidant property and needs further evaluation to exploit its therapeutic potential.
|Item Type:||Journal article(non-copyrighted)|
|Format:||PDF document, 224.96 KB|
|Keywords:||2; 2-Diphenyl-1-Picrylhydrazyl (DPPH); Minerals; Phytochemicals; Pterocarpus mildbraedii; Reducing power.|
|Field of Study:||Biochemistry|
|Uploaded By:||Imarhiagbe Odoligie|
|Date Added:||22 Nov 2017 11:04am|
|Last Modified:||22 Nov 2017|
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