SEASONAL VARIATION OF HEPATITIS B AND C VIRUS INFECTION AMONG HIV- AND NON-HIV-INFECTED PATIENTS IN BENIN CITY, NIGERIA
Dr Oladeinde Bankole Henry and Ifeoma M. Ekejindu2, Richard Omoregie (Published 2019)
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Introduction: Seasonal variation in immunity has been found in healthy individuals and in association with some diseases. Data on seasonal prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection is sparse. This study aimed at determining the seasonal seroprevalence of HBV and HCV infections among human immunodeficiency virus (HIV)-infected patients in Benin City.
Material and methods: A total of 1,177 HIV-positive and 503 non-HIV-positive patients were recruited for this study. Venous blood was collected from all participants and screened for the presence of HBsAg and anti-HCV antibody using immunochromatographic technique.
Results: The seroprevalence of HBV infection did not differ significantly with respect to season among HIV-infected patients (rainy season vs. dry season: 4.2% vs. 3.4%; OR = 1.271; 95% CI = 0.695-2.322;
p = 0.451), and non-HIV-infected patients (rainy season vs. dry season: 3.2% vs. 4.0%; OR = 0.783;
95% CI = 0.305-2.020; p = 0.639). A statistically significant association was however observed between HCV seropositivity and rainy season among HIV-infected patients only (rainy season vs. dry season: 3.9% vs. 1.1%; OR = 3.789, 95% CI = 1.537-9.342; p = 0.003).
Conclusions: HIV-infected patients in Nigeria are at risk of acquiring HCV infection during the rainy season. Control and prevention methods for HBV and HCV infections among HIV-infected patients are advocated.
|Item Type:||Journal article(non-copyrighted)|
|Format:||PDF document, 170.95 KB|
|Keywords:||MEDICAL LABORATORY SCIENCE|
|Department:||Medical Laboratory Science|
|Field of Study:||Medical Laboratory Science|
|Uploaded By:||Uwaifo Ferdinand|
|Date Added:||28 Feb 2019 12:25pm|
|Last Modified:||28 Feb 2019|
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