Lecture title: GENERAL EMBRYOLGY 2018/2019

Dr Odetola Amoo Amos   (Published 2019)

Dr Amoo Amos
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Lecture Note

Anatomy Department
ANA 201 General Embryolgy
Instructor: Dr. Odetola Amos A., email:odetola.amos@edouniversity.edu.ng
Lectures: Friday, 10 am- 12pm, LT1, phone: (+234) 8032072958
Office hours: Thursday, 1.30 to 2.30 PM, Office:
General overview of lecture: The course introduces some fundamental concepts in
developmental anatomy including molecular regulation and signaling, gametogenesis, prefertilization,
fertilization, cleavage, implantation, bilaminar germ disc and gastrulation
(Trilaminar germ layer stage).
Prerequisite: The students are expected to have a strong background in the basic biology,
particularly about the reproductive system.. Some knowledge of genetics will be of great
importance in understanding some concepts of teratology.
Learning outcomes: At the completion of this lecture, students should be able to:
• Enumerate various regulatory molecules that are involved in organogenesis
• describe the cell division
• mention the source of the primordial germ cells
• state the incident or occurrences during the 2nd week of development
• explain ovarian cycle, fertilization, cleavage and implantation in details
• understand the principles of teratology
Assignments: students are going to have three (2) individual and one (1) group assignments
throughout the course in addition to a Mid-Term Test and a Final Exam. Assignments are
organized and structured as preparation for the midterm and final exam, and are meant to be a
studying material for both exams.
Grading: We will assign 10% of this class grade to homeworks, 10% for the programming
projects, 10% for the mid-term test and 70% for the final exam. The Final exam is
Textbook: The recommended textbook for this class are as stated:
Title: Langman’s Medical Embryology
Author: T.W. Sadler
Publisher: Wolters Kluwer Health
ISBN: 978-1-4511-9164-6
Title: Larsen’s Human Embryology
Authors: Gary C.S., Steven B.B., Philip R.B., and Philippa H.F.
Publisher: Churchill Livingstone
ISBN: 978-1-4557-0684-6
Title: The Developing Human, Clinically Oriented Embryology 8th Ed.
Author: K.L. Moore and T.V.N.Persaud
Publisher: Saunders
Courseware: ANA 201 General Embryology
The following documents outline the courseware for the course ANA 213 General Embryology.
Much of this material is taken from recommended text books.
1:Introduction to Molecular Regulation and Signaling
§ Gene Transcription
§ Other regulation of gene expression
§ Induction and Organ formation
§ Cell signaling
§ Key Signaling Pathways for Development
§ What is Gametogenesis?
§ What is gamete and why the study of gamete?
§ Primordial Germ Cells
§ Chromosomal theory of inheritance
§ Morrphological changes during maturation of the gametes:Spermatogenesis& Oogenesis
3: First week of Development.
§ Ovarian cycle
§ Fertilization
§ Cleavage
§ Blastocyst formation
4: Second Week of Development: Bilaminar Germ Disc
§ Differentiation of trophoblast into cytotrophoblast and syncytiotrophoblast
§ Development of foetal membranes
§ Formation of two cavities: Amniotic and Chorionic cavities
§ Formation of somatic and splanchnic mesoderm
5: Third Week of Development
§ Gastrulation: formation of embryonic mesoderm and endoderm
§ Formation of the Notochord
§ Establishment of the body axes
§ Growth of the embryonic disc
6: 3rd to 8th Week of Development
§ Derivatives of Ectodermal Germ Layer
§ Derivatives of Mesodermal Germ Layer
§ Derivatives of Endodermal Germ Layer
§ Patterning of the Anteroposterior Axis

Item Type: Lecture note(non-copyrighted)
Format: PDF document,   151.97 KB
Copyright: Creative Commons LicenseCreative Commons license
Keywords: anatomy
Department: Medicine and Surgery
Field of Study: Human Anatomy
Uploaded By: Uwaifo Ferdinand
Date Added: 04 Feb 2019 7:33am
Last Modified: 04 Feb 2019
Lecture URL: https://www.edouniversity.edu.ng/oer/lecturenotes/general_embryolgy_20182019

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